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Zymycin (Azithromycin)
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Zymycin

Zymycin belongs to a group of Macrolide Antibiotics useful for treating numerous infections caused by bacteria like middle ear infections, traveler's diarrhea. Along with other medications, it is sometimes used for malaria. It is also used to treat a number of intestinal infections and sexually transmitted infections including gonorrhea and chlamydia. Administration of the medicine takes place either by mouth or intravenously with doses once per day.

Other names for this medication:
Atizor, Azalid, Azicip, Aziphar, Azithromycinum, Azithrus, Azitrin, Azitrix, Azitrotek, Azycyna, Bactexina, Ericiclina, Goldamycin, Goxil, Gramokil, Neofarmiz, Toraseptol, Trozocina, Unizitro, Vectocilina, Zibac, Zistic, Zithrin, Zithrocin, Zithrogen, Zocin

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Also known as: Azithromycin

Description

Zymycin (Zymycin tablets and Zymycin for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Zymycin has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Zymycin is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Zymycin, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Zymycin is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Zymycin for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

Dosage of Zymycin is setted individually according to nosology, disease severity and sensitivity of the pathogen. Dosage for adults for oral administration is 0.25-1 g 1 time/day; for children - 5-10 mg/kg 1 time/day. The duration of administration is 2-5 days.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Zymycin overdose may include nausea, vomiting, diarrhea, and stomach discomfort.

Storage

Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.

Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Zymycin Tablet.

Side effects

The most common side effects associated with Zymycin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Zymycin Z-Pak if you are allergic to it, or if you have ever had:

jaundice or liver problems caused by taking Zymycin Z-Pak; or a severe allergic reaction to similar drugs such as clarithromycin, erythromycin, or telithromycin.

Zymycin Z-Pak oral should not be used to treat pneumonia in people who have:

cystic fibrosis; an infection after being in a hospital; an infection in the blood; a weak immune system (caused by diseases such as HIV/AIDS or cancer); or in older adults and those who are ill or debilitated.

Tell your doctor if you have ever had:

pneumonia; liver or kidney disease; myasthenia gravis; low levels of potassium in your blood; a heart rhythm disorder; or long QT syndrome (in you or a family member).

It is not known whether this medicine is effective in treating genital ulcers in women.

Tell your doctor if you are pregnant or breastfeeding. Taking Zymycin Z-Pak while breastfeeding may cause diarrhea, vomiting, or rash in the nursing baby.

Zymycin Z-Pak is not approved for use by anyone younger than 6 months old. This medicine should not be used to treat a throat or tonsil infection in a child younger than 2 years old.

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Clinical aspects of twelve patients with benign mesenchymal lung tumours including four so-called sclerosing haemangiomas were studied. IL-4 knockout mice showed similar pulmonary pathology, but no increase in airway resistance, suggesting that IgE and hence IL-4 may be important in eliciting the airway response, while other factors may be involved in the inflammatory process. Membrane lipid depletion in hyperpermeable red blood cells: its role in the genesis of spherocytes in hereditary spherocytosis. Homogeneous reactions in general are relatively easy to study with respect to heterogeneous systems since all catalytic sites are uniform and can be addressed simultaneously. The process of AIDS education poses exceptional challenges for teachers and students. Skin biopsies were independently evaluated by 2 dermatopathologists who characterized the main histological patterns and scored dermal and epidermal changes, which were further correlated with clinical and laboratorial data. Crystal structure and magnetic property of composite particles are examined using electron microscopy, x-ray diffractometer and vibration sample magnetometer.

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Management of true aneurysms of the pancreaticoduodenal arteries. The stimulus was a train of electrical pulses delivered to individual ABI electrodes via a research interface. One hundred and twelve young adolescents, their mothers, and their social studies teachers served as participants. The enrichment or depletion of B cells from the transferred T cells had no measurable effect upon the development of a healing response in reconstituted scid mice. After adjustment for serum creatinine, positive correlations of serum uric acid with body weight and fasting blood glucose in women and with serum cholesterol in men were significant. A virus mutant lacking gL, PrV-DeltagLbeta, is defective in entry into target cells, and direct cell-to-cell spread is drastically reduced, resulting in only single or small foci of infected cells (B.

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A self-administered questionnaire, previously validated in two nonsampled schools, was administered in selected classes by the pediatrician leading the project. Literature has shown that obesity, metabolic syndrome and inflammation are associated with depression, however, evidence suggests that these associations are specific to atypical depression. Proteolysis of human growth hormone by rat thyroid gland in vitro: application of electrospray mass spectrometry and N-terminal sequencing to elucidate a metabolic pathway. To our knowledge, there are only four previously described instances of testicular Brenner tumors. The difference in the film thickness reflects the effects of Rayleigh and Marangoni convection, and the water vapor flow rate reveals the role of viscous fingering in the emergence of aligned FF flakes.

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Diagnosis of Latent Tuberculosis Infection: Too Soon to Pull the Plug on the Tuberculin Skin Test. Implenting family planning in a Ministry of Health: organizational barriers at the state and district levels. Cytospectrophotometric study of GABA-transaminase in the rat cerebellar cortex. The drugs represent a new promising pharmacological class of agents used for postsurgical adjuvant treatment of cancer. A safety culture training program enhanced the perceptions of patient safety culture of nurse managers. Although both the anti-angiogenic agents (AAs) and the vascular disrupting agents (VDAs) target tumor vasculature, they differ in their mechanism of action and therapeutic application. These results suggest that genetic influences on the body weight of infants may be independent of those that influence BMI in adults, a circumstance that could complicate the search for genetic determinants of obesity.

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The use of intraoperative triggered electromyography to detect misplaced pedicle screws: a systematic review and meta-analysis. Following nerve transection, acetylcholinesterase activity is diminished, and SPL-immunoreactivity increased in the affected motoneurons. Our experimental strategy represents an efficient approach to the identification and interspecies comparison of genes encoding products targeted to the mitochondrion. Leech segmentation: cell lineage and the formation of complex body patterns. A recombinant fowlpox virus (rFPV/E2) expressing the E2 protein of bovine viral diarrhea virus (BVDV) was constructed and characterized.

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