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Zymycin (Azithromycin)

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Zymycin belongs to a group of Macrolide Antibiotics useful for treating numerous infections caused by bacteria like middle ear infections, traveler's diarrhea. Along with other medications, it is sometimes used for malaria. It is also used to treat a number of intestinal infections and sexually transmitted infections including gonorrhea and chlamydia. Administration of the medicine takes place either by mouth or intravenously with doses once per day.

Other names for this medication:
Atizor, Azalid, Azicip, Aziphar, Azithromycinum, Azithrus, Azitrin, Azitrix, Azitrotek, Azycyna, Bactexina, Ericiclina, Goldamycin, Goxil, Gramokil, Neofarmiz, Toraseptol, Trozocina, Unizitro, Vectocilina, Zibac, Zistic, Zithrin, Zithrocin, Zithrogen, Zocin

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Also known as: Azithromycin


Zymycin (Zymycin tablets and Zymycin for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Zymycin has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Zymycin is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Zymycin, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Zymycin is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Zymycin for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.


Dosage of Zymycin is setted individually according to nosology, disease severity and sensitivity of the pathogen. Dosage for adults for oral administration is 0.25-1 g 1 time/day; for children - 5-10 mg/kg 1 time/day. The duration of administration is 2-5 days.


Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Zymycin overdose may include nausea, vomiting, diarrhea, and stomach discomfort.


Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.

Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Zymycin Tablet.

Side effects

The most common side effects associated with Zymycin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Zymycin Z-Pak if you are allergic to it, or if you have ever had:

jaundice or liver problems caused by taking Zymycin Z-Pak; or a severe allergic reaction to similar drugs such as clarithromycin, erythromycin, or telithromycin.

Zymycin Z-Pak oral should not be used to treat pneumonia in people who have:

cystic fibrosis; an infection after being in a hospital; an infection in the blood; a weak immune system (caused by diseases such as HIV/AIDS or cancer); or in older adults and those who are ill or debilitated.

Tell your doctor if you have ever had:

pneumonia; liver or kidney disease; myasthenia gravis; low levels of potassium in your blood; a heart rhythm disorder; or long QT syndrome (in you or a family member).

It is not known whether this medicine is effective in treating genital ulcers in women.

Tell your doctor if you are pregnant or breastfeeding. Taking Zymycin Z-Pak while breastfeeding may cause diarrhea, vomiting, or rash in the nursing baby.

Zymycin Z-Pak is not approved for use by anyone younger than 6 months old. This medicine should not be used to treat a throat or tonsil infection in a child younger than 2 years old.

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Why are urinary tract infections so common in diabetes mellitus?. Surprisingly, endogenous endophthalmitis accounted for almost one fifth of all cases. A similar increase was seen in uteri from ovariectomized, hypophysectomized rats treated with E2. The familial carcinoma burden and indications for subcutaneous mastectomy. In contrast, there was little change in the level of GLUT-3 mRNA when the cells were cultured in the presence of 5 mmol/l galactose. Current bibliographies of neuropeptides prepared by the University of Sheffield Biomedical Information Service. The survey assessed familiarity, knowledge, attitudes, benefits, barriers, concerns and use of educational enablers around the NCPT. Transsphenoidal surgery was performed in 11 patients over 70 years of age affected by various histological types of pituitary micro- and macroadenomas, ranging from Hardy Grade I through IIIc. The main drivers of narrowing and widening mortality inequalities were cerebrovascular disease and suicide, respectively.

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In cultures at a specific stage, proflavine showed decreased mutagenesis in a recA as compared with a wildtupe or uvrB derivative. Functional characterization of a VEGF-A-targeting Anticalin, prototype of a novel therapeutic human protein class. We modeled nitrogen dioxide (NO2) and noise from road traffic (Lden) exposure at all pregnancy addresses. Finally an analysis of the impairments to peripheral writing processes, i.e. Empirical conformational energy calculations were carried out for the dipeptides cyclo-(L-Ser-L-His) and cyclo-(L-Thr-L-His). In this work, we propose a probabilistic label fusion framework based on atlas label confidences computed at each voxel of the structure of interest. Thus, FIV infection may be an excellent animal model in which to study human immunodeficiency virus and should be considered in the differential diagnosis of cats with chronic leukopenia. 123I-SCH 23982 is not suitable for dopamine D1 receptor imaging in vivo in the human brain.

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Clinical aspects of twelve patients with benign mesenchymal lung tumours including four so-called sclerosing haemangiomas were studied. IL-4 knockout mice showed similar pulmonary pathology, but no increase in airway resistance, suggesting that IgE and hence IL-4 may be important in eliciting the airway response, while other factors may be involved in the inflammatory process. Membrane lipid depletion in hyperpermeable red blood cells: its role in the genesis of spherocytes in hereditary spherocytosis. Homogeneous reactions in general are relatively easy to study with respect to heterogeneous systems since all catalytic sites are uniform and can be addressed simultaneously. The process of AIDS education poses exceptional challenges for teachers and students. Skin biopsies were independently evaluated by 2 dermatopathologists who characterized the main histological patterns and scored dermal and epidermal changes, which were further correlated with clinical and laboratorial data. Crystal structure and magnetic property of composite particles are examined using electron microscopy, x-ray diffractometer and vibration sample magnetometer.

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The presence of this pseudogene raises the question as to whether atp8 is encoded in some bivalve mitochondrial genomes or not. Instead of thousands of pixel-wise variables, this Lorentzian-sparsity method significantly reduces the number of unknowns to several geometric variables, such as the center, magnitude and shape parameters for each Lorentzian function. Examining an affect regulation model of substance abuse in schizophrenia. Changes in the hip joint caused by asymmetry of the lower limbs. The diagnostic value of contrast-enhanced ultrasound (CEUS) as a new technique for imaging of vascular complications in renal transplants compared to standard imaging modalities. No complications resulting from the administration of the drug were observed.

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To find out whether a pertussis sensitive mechanism is involved in the regulation of the cGMP-system, bovine mesenteric arteries were incubated in buffer containing pertussis toxin, and the relaxation and intracellular cGMP accumulation induced by different groups of vasodilating agents were studied. Preincubation of platelets with ascorbate blocked the oxidation of tocopherol. The authors examined three groups of children for minor physical anomalies: 52 autistic children, 34 nonautistic siblings of these patients, and 29 normal controls. The diagnosis was confirmed in 118 patients, and they were studied by two-dimensional and Doppler echocardiography. Induction of acid tolerance by L-glutamate was associated with the accumulation in the growth medium of a protein (or proteins) which was able to convert pH 7.0-grown cultures to acid tolerance, and the original L-glutamate-induced tolerance response was dependent on this component(s). Dry matter intake, fat-corrected milk yield, daily fat production, and solids-not-fat did not differ between diets. Sixty-one Duroc, 24 Landrace, 18 Duroc x Landrace, and 16 three- and four-breed crossbred litters were weighed every 3 or 4 d from 13 to 30 d of age.

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Management of true aneurysms of the pancreaticoduodenal arteries. The stimulus was a train of electrical pulses delivered to individual ABI electrodes via a research interface. One hundred and twelve young adolescents, their mothers, and their social studies teachers served as participants. The enrichment or depletion of B cells from the transferred T cells had no measurable effect upon the development of a healing response in reconstituted scid mice. After adjustment for serum creatinine, positive correlations of serum uric acid with body weight and fasting blood glucose in women and with serum cholesterol in men were significant. A virus mutant lacking gL, PrV-DeltagLbeta, is defective in entry into target cells, and direct cell-to-cell spread is drastically reduced, resulting in only single or small foci of infected cells (B.

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The ultrastructure of tachyzoites of 3 isolates of Neospora caninum from dogs was examined, using transmission electron microscopy of infected cultured cells. The short-term use of luteinising hormone-releasing hormone analogues in uterine fibroids. A novel tool for continuous fracture aftercare - Clinical feasibility and first results of a new telemetric gait analysis insole. Comparative studies by administration of tuberculin RT-23 in doses 1 TU and 2 TU (Epidemiologic part). In the marrow culture, both rhIL-1 alpha and rhIL-1 beta stimulated osteoclastlike cell formation, which was completely inhibited propecia prices by adding indomethacin concurrently. Generalized neuronal defects and intensive degenerative lesions in the preserved neurons with signs of decomposition of fibrous elements of tissular basis followed an administration of quinolinic acid in the dose of 100 mol/ml for 4 and 8 consecutive days. An extreme thermophile, Thermus thermophilus HB 8, contains two types of tRNAs, T- and S2T-containing tRNAs. No inhibiting effect of LMIF on the leukocytes in these patients appears to be due to the defect of the target cells and not of the producer cells. Important issues pertain to trial design, duration of follow-up, the role of placebo effects, side effects, and confounding variables. In the present study the possible influence of the antacid Maalox on the pharmacokinetics of capecitabine (Xeloda) and its metabolites was investigated in cancer patients.

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This study indicates that dawn simulation is an effective treatment for winter depression. This section reviews the anatomy and physiology, pathophysiology, and clinical and laboratory findings in pulmonary disorders. The properties of gelatinases secreted in culture medium of murine fibroblasts, macrophages, colonic carcinoma, FBJ virus-induced osteosarcoma, Lewis lung carcinoma and mammary tumor cells were compared. In every case, urticarial manifestation cleared up after either healing or controlling of the viral infection. Sixty-four control subjects from the general eye clinic were evaluated in the same manner. Compound 27g was also significantly more selective against other kinases than 4. However, such sequences may be involved in gene conversion events. Effects of diazepam (1, 2 mg/kg) and buspirone (1.25, 2.5 mg/kg) on locomotor and rearing activity were observed in rats tested in an open field.

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A self-administered questionnaire, previously validated in two nonsampled schools, was administered in selected classes by the pediatrician leading the project. Literature has shown that obesity, metabolic syndrome and inflammation are associated with depression, however, evidence suggests that these associations are specific to atypical depression. Proteolysis of human growth hormone by rat thyroid gland in vitro: application of electrospray mass spectrometry and N-terminal sequencing to elucidate a metabolic pathway. To our knowledge, there are only four previously described instances of testicular Brenner tumors. The difference in the film thickness reflects the effects of Rayleigh and Marangoni convection, and the water vapor flow rate reveals the role of viscous fingering in the emergence of aligned FF flakes.

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Three-dimensional models of the pelvis were reconstructed using software from computed tomography images of whole specimens. Propofol injection pain is a common problem that can be very distressing for patients. The ultrastructure of the hepatic tissue was observed by electron microscopy. Recommendations were made to the World Health Organization, which include the use of appropriate small animal models prior to studies in non-human primates, restricting the use of chimpanzees to the final stages of vaccine testing after a prototype SIV vaccine has been shown to prevent infection, and gathering information on safety and efficacy in animal models prior to the initiation of phase I trials in humans. Necropsy revealed an irregular mass circumferentially lining the left ventricular outflow tract as well as multiple myocardial metastases. Ion release, fluoride charge of and adhesion of an orthodontic cement paste containing microcapsules. Educating the elderly: cardiopulmonary resuscitation decisions before and after intervention. An explant of human prostate tissue containing viable acini will give rise in vitro to an outgrowth of epithelial cells of presumed basal cell compazine ivp dose origin. Smith, Jr, MD, Professor of Medicine and Associate Dean in the School of Medicine.

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Diagnosis of Latent Tuberculosis Infection: Too Soon to Pull the Plug on the Tuberculin Skin Test. Implenting family planning in a Ministry of Health: organizational barriers at the state and district levels. Cytospectrophotometric study of GABA-transaminase in the rat cerebellar cortex. The drugs represent a new promising pharmacological class of agents used for postsurgical adjuvant treatment of cancer. A safety culture training program enhanced the perceptions of patient safety culture of nurse managers. Although both the anti-angiogenic agents (AAs) and the vascular disrupting agents (VDAs) target tumor vasculature, they differ in their mechanism of action and therapeutic application. These results suggest that genetic influences on the body weight of infants may be independent of those that influence BMI in adults, a circumstance that could complicate the search for genetic determinants of obesity.

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The use of intraoperative triggered electromyography to detect misplaced pedicle screws: a systematic review and meta-analysis. Following nerve transection, acetylcholinesterase activity is diminished, and SPL-immunoreactivity increased in the affected motoneurons. Our experimental strategy represents an efficient approach to the identification and interspecies comparison of genes encoding products targeted to the mitochondrion. Leech segmentation: cell lineage and the formation of complex body patterns. A recombinant fowlpox virus (rFPV/E2) expressing the E2 protein of bovine viral diarrhea virus (BVDV) was constructed and characterized.

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